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IDE 196-002
IDE196 (Darovasertib) in Combination with Crizotinib Versus Investigator·s Choice of Treatment as First-line Therapy in HLA-A2 Negative Metastatic Uveal Melanoma (DAR-UM-2).
- Ouvert à Paris depuis le : 07/10/2024
- Public cible : Adult
- Phase : Phase II/III
Description de l'essai
Phase 2a: To determine the;optimal dose of IDE196 +;crizotinib combination in Phase 2a;in order to achieve the;recommended dose for Phase 2b;and Phase 3;Phase 2b: To compare IDE196 +;crizotinib to investigatorÀs choice;of treatment with respect to PFS;per RECIST 1.1 as assessed by;blinded independent central review;(BICR)
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