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Unit
Immunity and Cancer (U932)
Présentation
Created in 2005, the INSERM U932 Unit is composed of 10 teams, spread over two buildings (Hôpital Curie and Constant-Burg building, rue Lhomond), with a total of about 120 people.
The teams of our department try to better understand the immune responses, and to direct the immune system to better fight against pathogens and/or tumours. Research projects range from fundamental immunology to translationnal immunology and cancer immunotherapy. These approaches include biology, biochemistry and molecular imaging techniques, based on both in vitro and in vivo experimental models, and immunological monitoring, diagnosis, prognosis and immunotherapy studies in cancer patients.
- Immune responses and cancer (S. AMIGORENA)
- Myeloid cells and immunity (P. BENAROCH)
- Integrative analysis of T cell activation (C. HIVROZ)
- Innate like and CD4+ T cells in cancer (O. LANTZ)
- Spatio-temporal dynamics of immune cells (A.M. LENNON)
- Innate immunity (N. MANEL)
- Translational immunotherapy (E. PIAGGIO)
- Stem cell immunity (E.POIRIER)
- Stroma and immunity (H. SALMON)
- Extracellular vesicles, immune responses and cancer (C. THERY)
Axes de recherche thématiques
Équipes
Publications clés
2023Nuclear envelope disruption triggers hallmarks of aging in lung alveolar macrophages
Nature Aging - 18/09/2023
Voir les auteurs
2023Epigenetically controlled tumor antigens derived from splice junctions between exons and transposable elements
Science Immunology - 24/02/2023
Voir les auteurs
2022Epithelial colonization by gut dendritic cells promotes their functional diversification
Immunity - 01/01/2022
Voir les auteurs
2021Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9
Nature Communications - 01/12/2021
Voir les auteurs
2020Macrophages Maintain Epithelium Integrity by Limiting Fungal Product Absorption
Cell - 01/10/2020
Voir les auteurs
2019Clonally Expanded T Cells Reveal Immunogenicity of Rhabdoid Tumors
Cancer Cell - 01/12/2019
Voir les auteurs
2019Microbial metabolites control the thymic development of mucosal-associated invariant T cells
Science - 25/10/2019
Voir les auteurs
2019Constitutive Siglec-1 expression confers susceptibility to HIV-1 infection of human dendritic cell precursors
Proceedings of the National Academy of Sciences - 22/10/2019
Voir les auteurs
2018NONO Detects the Nuclear HIV Capsid to Promote cGAS-Mediated Innate Immune Activation
Cell - 01/10/2018
Voir les auteurs
2018Rab6-dependent retrograde traffic of LAT controls immune synapse formation and T cell activation
Journal of Experimental Medicine - 02/04/2018
Voir les auteurs
2018The epigenetic control of stemness in CD8
+
T cell fate commitment
Science - 12/01/2018
Voir les auteurs
2017Qualitative differences in T‐cell activation by dendritic cell‐derived extracellular vesicle subtypes
The EMBO Journal - 16/10/2017
Voir les auteurs
Vie d'équipe
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Voir les autres offres d'emploi du Centre de RechercheÉvénements scientifiques
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23/06/2026 09:00 - 20:00
Centre de recherche - Paris - Amphithéâtre Constant-Burg - 12 rue Lhomond, Paris 5e
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24/02/2026 11:00 - 12:00
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23/01/2026 11:00 - 23:59
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09/01/2026 10:00 - 23:59
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SéminaireImpaired Polyamine Metabolism Drives Hematopoietic Aging
Orateurs : Nader YATIM
15/12/2025 11:00 - 23:59
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Séminaire Immunology seriesInter-Individual TCR repertoire diversity of epitope-specific CD8+ T cell populations
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28/11/2025 10:00 - 23:59
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21/11/2025 11:00 - 12:00
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04/11/2025 11:00 - 23:59
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24/10/2025 11:00 - 23:59
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Séminaire Immunology seriesLipid nanoparticles for mRNA vaccine delivery
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03/10/2025 11:00 - 23:59
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SéminaireThe transcription factor AFF3 maintains naïve CD8 T cell quiescence restraining premature cell activation allowing for optimal T cell response to viral infection.
Orateurs : Molly LUMNITZER
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Centre de recherche - Paris - Amphithéâtre Marie Curie
SéminaireDissecting the crossroads of circulating and tissue-resident T cells in solid tumors
Orateurs : Alvaro IIADSER
08/09/2025 11:00 - 23:59
Centre de recherche - Paris - Amphithéâtre Constant-Burg - 12 rue Lhomond, Paris 5e
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05/09/2025 11:00 - 23:59
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SéminaireUnexpected diversity of the thymic antigen presenting cell network and the implications for T cell development
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16/07/2025 11:00 - 23:59
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16/06/2025 11:00 - 23:59
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SéminaireThe dual role of inflammation in cancer immunity
Orateurs : Santiago ZELENAY
28/05/2025 11:00 - 23:59
Centre de recherche - Paris - Amphithéâtre Constant-Burg - 12 rue Lhomond, Paris 5e
SéminaireRegenerating thymic T-cell production after bone marrow transplantation and during aging
Orateurs : Magali IRLA
26/05/2025 15:00 - 23:59
Centre de recherche - Paris - Amphithéâtre Constant-Burg - 12 rue Lhomond, Paris 5e
Séminaire Immunology seriesThe afterlife: decoding the response when cells die
Orateurs : Carla Rothlin
14/05/2025 11:00 - 23:59
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Centre de recherche - Paris - Amphithéâtre Constant-Burg - 12 rue Lhomond, Paris 5e
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28/04/2025 11:00 - 23:59
Centre de recherche - Paris - Amphithéâtre Constant-Burg - 12 rue Lhomond, Paris 5e
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Centre de recherche - Paris - Amphithéâtre Constant-Burg - 12 rue Lhomond, Paris 5e
SéminairePublishing in Science Immunology: An Inside Look
Orateurs : Seth Scanlon
03/02/2025 15:00 - 16:00
Hôpital site de Paris - Amphithéâtre Constant-Burg - 12 rue Lhomond, Paris 5e
Séminaire Immunology seriesTranscriptional control of mononuclear phagocytes in homeostasis and disease
Orateurs : Bart Lambretch
24/01/2025 11:00 - 23:59
Hôpital site de Paris - Amphithéâtre Constant-Burg - 12 rue Lhomond, Paris 5e
SéminaireTreg stability and function in the tumor environment
Orateurs : Benoit Salomon
09/12/2024 11:00 - 23:59
Centre de recherche - Paris - Amphithéâtre Constant-Burg - 12 rue Lhomond, Paris 5e
SéminaireTHE NEUTROPHIL NUCLEUS AS A SIGNALING HUB DURING CHEMOTAXIS AND DNA RELEASE
Orateurs : Carole Parent
18/11/2024 11:00 - 23:59
Centre de recherche - Paris - Amphithéâtre Constant-Burg - 12 rue Lhomond, Paris 5e
SéminaireChromosome and chromatin dynamics at DNA double Strand breaks
Orateurs : Gaëlle Legube, ,
05/11/2024 11:00 - 23:59
Centre de recherche - Paris - Amphithéâtre Constant-Burg - 12 rue Lhomond, Paris 5e
Séminaire Immunology seriesAuto immune mechanisms in Parkinsons disease
Orateurs : Michel Desjardins
28/10/2024 11:00 - 23:59
Centre de recherche - Paris - Amphithéâtre Constant-Burg - 12 rue Lhomond, Paris 5e
SéminaireWhy immunologists have no other choice but to do conceptual & theoretical immunology
Orateurs : Thomas Pradeu
23/09/2024 11:30 - 23:59
Centre de recherche - Paris - Amphithéâtre Hélène Martel-Massignac (BDD)
Séminaire Immunology seriesWhen Nuance Matters: The lesser known side of PD1 signaling
Orateurs : Enfu Hui
16/09/2024 11:00 - 23:59
Centre de recherche - Paris - Amphithéâtre Constant-Burg - 12 rue Lhomond, Paris 5e
SéminaireB cell memory in barrier tissues - " From the bench to the bedside: cancer immunotherapy with soluble T cell receptors"
Orateurs : Mauro Gaya, Mariolina Salio
10/09/2024 14:00 - 23:59
Centre de recherche - Paris - Amphithéâtre Marie Curie
SéminaireFunctional and molecular characterization of cancer-derived extracellular vesicles
Orateurs : Dolores Di Vizio
10/06/2024 11:00 - 23:59
Centre de recherche - Paris - Amphithéâtre Constant-Burg - 12 rue Lhomond, Paris 5e
SéminaireNucleosomes and DNA methylation implications for immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome and cancers
Orateurs : Hironori Funabiki
21/05/2024 11:00 - 23:59
Centre de recherche - Paris - Amphithéâtre Constant-Burg - 12 rue Lhomond, Paris 5e
SéminaireDeconstruct-Reconstruct Decode cancer-immune crosstalk & probe with organoids
Retrouvez tous les prochains événements scientifiques Orateurs : Jeroen Roose
13/05/2024 11:00 - 23:59
Hôpital site de Paris - Amphithéâtre Hélène Martel-Massignac (BDD)
Actualités
Research
Institut Curie contributes to four Université PSL Major Research Programs to tackle key challenges in biology and health
14/09/2026
Celebration
The Immunity and Cancer research unit (U932) celebrates its twentieth anniversary
12/12/2025
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